Natto contains fiber, probiotics, vitamin K2 and nattokinase. This combination can help lower cholesterol and blood pressure levels and lower the risk of heart disease. Intervention with serrapeptase and nattokinase to alleviate the physiopathology of Alzheimer's disease in a rat model. Therefore, this study aims to evaluate the efficacy of nattokinase in cardiovascular risk factors and provide evidence-based recommendations for clinical decision-making. If you have difficulty swallowing pills, nattokinase may also be available in other dosage forms, such as powder.
It should be noted that, in the meta-analysis of a relatively high total dose of nattokinase supplements, an increase in HDL-C and a decrease in LDL-C were detected among the participants included. Third, a quantitative analysis of the antithrombotic and anticoagulant effects of nattokinase was lacking. Before taking nattokinase, contact your pharmacist or healthcare provider to help you achieve your health goals safely. In addition to reducing stroke risk factors, such as high blood pressure and blood clots, nattokinase is associated with a decrease in von Willebrand factor (vWF) in people assigned as women at birth.
More high-quality research is needed with larger, well-designed clinical trials to evaluate the efficacy and safety of nattokinase. Nattokinase (NK), the most active ingredient in natto, has several favorable cardiovascular effects and its consumption has been linked to a reduction in mortality from cardiovascular diseases. However, due to the existing limitations of this work, these findings could be considered preliminary and a definitive conclusion could not be reached as to whether nattokinase supplementation was closely related to improvement of any cardiovascular risk factor. In 1987, Sumi et al3 discovered that natto contained a potent fibrinolytic enzyme called nattokinase (NK).
Natto is a famous traditional Japanese food made from fermented soybeans, containing a variety of functional ingredients, including nattokinase. Therefore, for future research, it is important to determine whether the lipid-lowering efficacy of nattokinase is dose-dependent. Therefore, nattokinase consumption is increasing in healthy people and people with cardiovascular diseases around the world, especially in Asian countries.
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