Nattokinase is a natural part of a Japanese soy food called natto. As a drug, nattokinase has been most commonly used in adults at doses of 2000 to 7000 oral fibrinolytic units per day for up to 3 years. Talk to a healthcare provider to find out what dose might be best for a specific condition. Nattokinase may help prevent blood clots, lower blood pressure, and play a role in treating Alzheimer's disease.
There is no safe and effective dose of nattokinase because no studies have been conducted with sufficient strength to find one. That said, several clinical studies have yielded beneficial results with various doses. In addition, a high dose of nattokinase was as effective in reducing blood clots as a known anticoagulant agent (vermis kinase). Nattokinase has also minimized acetylcholinesterase activity and the inflammatory markers associated with neurodegenerative diseases.
Studies show that nattokinase dissolves blood clots, helping to maintain good blood vessel structure, improving blood flow, and reducing the risk of heart disease. Before taking nattokinase, contact your pharmacist or healthcare provider to help you safely achieve your health goals. Patients with bleeding disorders and those currently receiving anticoagulant, fibrinolytic, or antithrombotic treatments should avoid nattokinase (. A small clinical trial on nattokinase in people without cardiovascular diseases found no significant benefit in prevention.
Of heart diseases. In a study of 12 healthy adult men, a single dose of nattokinase degraded fibrin and decreased levels of clotting factors, which are involved in blood clotting. Although research is still ongoing, animal studies show that nattokinase can degrade amyloid fibrils. These fibrous proteins bind to each other and are involved in the progression of Alzheimer's and Parkinson's diseases. Nattokinase is generally safe, but the enzyme's powerful effects can cause complications in people with specific health problems.
A combination of nattokinase and red yeast rice lowered cholesterol more effectively than nattokinase alone. Nattokinase, also known as natto extract (subtilisin NAT or urokinase), is an enzyme from natto, a fermented soy product. In addition to reducing stroke risk factors, such as high blood pressure and blood clot formation, nattokinase is associated with a decrease in von Willebrand factor (vWF) in people assigned at birth as women. And about one study, nattokinase had no side effects in several clinical trials.
After 60 days of nattokinase supplementation, participants were able to control their blood pressure and cholesterol better, in addition to improving their physical activity and their quality of life. Natto is rich in proteins, vitamins, and minerals, but most of the health benefits of food are related to its powerful enzyme nattokinase.
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