Which is better aspirin or nattokinase?

Aspirin has an average rating of 7.8 out of 10 out of a total of 47 ratings on Drugs, com.

Nattokinase

has an average rating of 7.0 out of 10 out of a total of 5 ratings on Drugs, com. We present the case of a patient who had used aspirin for the secondary prevention of a stroke and who suffered acute cerebellar bleeding after taking 400 mg of nattokinase a day for 7 consecutive days. All of the above data suggest that NK may be a good candidate, with no obvious adverse effects, to improve blood flow and possibly be superior to aspirin.

However, taking nattokinase can increase the effects of aspirin, which could cause an unexpected amount of bleeding. In the near future, patients with CVD may only need one NK pill to replace several drugs administered for the prevention and treatment of CVD, including tPA, antihypertensive drugs, statins, aspirin, and warfarin. However, long-term use of aspirin leads to serious gastrointestinal (GI) side effects and bleeding. Aspirin in low doses (85-100 mg daily), as a powerful anticoagulant agent, is widely used for the prevention of heart attacks, strokes and atherothrombotic diseases.

Aspirin treatment may be helpful in preventing a second or third heart attack, but for people who have never had one, the risks outweigh the benefits.